Международный эндокринологический журнал Том 14, №8, 2018
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Перспективы использования ресвератрола для лечения сахарного диабета и его осложнений
Авторы: Соколова Л.К., Пушкарев В.М.
ГУ «Институт эндокринологии и обмена веществ имени В.П. Комиссаренко НАМН Украины», г. Киев, Украина
Рубрики: Эндокринология
Разделы: Справочник специалиста
Версия для печати
Ресвератрол характеризується широким спектром фармакологічних ефектів і має множинну біологічну активність щодо хронічних захворювань, як протизапальний, протипухлинний, антидіабетичний, нейро- і кардіопротекторний засіб. Ресвератрол здійснює позитивний ефект при цукровому діабеті (ЦД) та діабетичних ускладненнях судин, що обумовлено його здатністю посилювати опосередковану оксидом азоту вазодилатацію. Продукти, багаті на ресвератрол, надають захисний ефект при таких вікових захворюваннях, як ЦД 2-го типу, атеросклероз, рак, артрит, катаракта, остеопороз, артеріальна гіпертензія і хвороба Альцгеймера. Ефекти ресвератролу свідчать про його перспективність як дієтичної добавки, що дозволяє поліпшити стан хворих на тяжкі хронічні захворювання, а також для профілактики цих захворювань у здорових людей і уповільнення процесів старіння.
Ресвератрол характеризуется широким спектром фармакологических эффектов и обладает множественной биологической активностью в отношении хронических заболеваний, как противовоспалительное, противоопухолевое, антидиабетическое, нейро- и кардиопротекторное средство. Ресвератрол оказывает положительный эффект при сахарном диабете (СД) и диабетических осложнениях сосудов, что обусловлено его способностью усиливать опосредованную оксидом азота вазодилатацию. Продукты, богатые ресвератролом, оказывают защитный эффект при таких возрастных заболеваниях, как СД 2-го типа, атеросклероз, рак, артрит, катаракта, остеопороз, артериальная гипертензия и болезнь Альцгеймера. Эффекты ресвератрола свидетельствуют о его перспективности в качестве диетической добавки, позволяющей улучшить состояние больных тяжелыми хроническими заболеваниями, а также для профилактики этих заболеваний у здоровых людей и замедления процессов старения.
Resveratrol is characterized by a wide range of pharmacological effects and has multiple biological activity against chronic diseases, as an anti-inflammatory, antitumor, antidiabetic, neuro- and cardioprotective agent. Resveratrol has a positive effect in diabetes mellitus and diabetic vascular complications, due to its ability to enhance nitrogen oxide-mediated vasodilation. Resveratrol-rich foods have a protective effect on age-related diseases such as type 2 diabetes mellitus, atherosclerosis, cancer, arthritis, cataract, osteoporosis, hypertension, and Alzheimer’s disease. The effects of resveratrol indicate its potential as a dietary supplement, allowing improve the condition of patients with severe chronic diseases, as well as for the prevention of these diseases in healthy people and slowing down the aging process.
ресвератрол; цукровий діабет; атеросклероз; рак; старіння; артеріальна гіпертензія; хвороба Альцгеймера
ресвератрол; сахарный диабет; атеросклероз; рак; старение; артериальная гипертензия; болезнь Альцгеймера
resveratrol; diabetes mellitus; atherosclerosis; cancer; aging; hypertension; Alzheimer’s disease
Важнейшие эффекты ресвератрола в организме здоровых людей и при различных заболеваниях
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